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Seizure activity results in calcium- and mitochondria-independent ROS production via NADPH and xanthine oxidase activation

Explore the CVOT study for RYBELSUS PIONEER 6: cardiovascular safety 6,7 Study design: In a double-blind trial, 3183 adult patients with inadequately controlled type 2 diabetes at high CV risk (50 years of age with CVD or CKD, or 60 with at least 1 CV risk factor) were randomized to RYBELSUS 14 mg (n=1591) or placebo (n=1592), both once daily and in addition to standard of care for a median observation time of 16 months

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If you take any of the following medications, you might be at risk of serotonin syndrome, or too much serotonin in the brain, if you take sertraline: Stimulants, such as ritalin Monoamine oxidase inhibitors (MAOIs) including any herbal medications that might contain MAOIs