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Upon inhalation, PAHs are bioactivated by cytochrome P450 (CYP450) enzymes, converting them into highly reactive electrophiles such as diol-epoxides and redox-active quinones

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10.1016/j.fertnstert.2009.12.079 66

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Women experiencing moderate to severe hot flashes, particularly those who are unable or unwilling to take hormone replacement therapy, might find relief with GLP-1s