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Alzheimers disease (AD) is the most common neurodegenerative disorder characterized by cognitive impairment, and iron levels in the hippocampus, which are severely impaired in AD patients, are significantly elevated 59

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Unbiased clustering identified 19 transcriptionally distinct cell populations, representing five major lineages: T/NK cells, monocytes/macrophages, fibroblasts, eosinophils and neutrophils (Figs