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Furthermore, exendin-4 administration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in vivo animal model of PD has been shown to inhibit microglial activation thereby minimizing the loss of dopaminergic neurons in the pars compacta of the substantia nigra and the striatum [78]

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Ethical Considerations and Regulatory Compliance All peptide research must be conducted with strict adherence to ethical guidelines and relevant regulatory frameworks

doi: 10.3233/JAD-2009-0963 398 WozniakM