On July 10, 2024, Kuei-Pin Huang and colleagues published a paper in Nature titled Dissociable Hindbrain GLP1R Circuits for Satiety and Aversion. The study suggests that future weight loss medications could selectively target GLP1R neurons in the nucleus of the solitary tract (NTS) to avoid inducing aversion, thereby improving treatment adherence and effectiveness [1]
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The Y2 receptor is the primary target receptor for PYY(3-36)
Finally, we will review emerging evidence that links alterations in cellular metabolism to the pathobiology of common respiratory diseases, including chronic obstructive pulmonary disease (COPD), asthma, and pulmonary fibrosis
nih Jastreboff A.M., Kaplan L.M., Fras J.P., Wu Q., Du Y., Gurbuz S., Coskun T., Haupt A., Milicevic Z., Hartman M.L