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Embora a Tirzepatida no tenha aprovao especfica para tratar dislipidemia e hipertenso, estudos clnicos indicam benefcios adicionais, como por exemplo: Reduo do colesterol LDL (ruim) em 5,8% (versus 1,7% com placebo)

In inflammation, IL-10 can reduce the antigen-presenting function by downregulating the expression of Mononuclear Cell Surface II major histocompatibility antigens (Class II major histocompatibility complex, MHC II), and inhibit inflammatory cell activation, migration, and adhesion by downregulating the activity of T cells

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Pushing to 2.4mg purely because it is the "maximum" dose is not always the right move, especially if side effects significantly impact quality of life