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Joel Habener Massachusetts General Hospital Lotte Bjerre Knudsen Novo Nordisk Svetlana Mojsov The Rockefeller University For the discovery and development of GLP-1-based drugs that have revolutionized the treatment of obesity The 2024 Lasker~DeBakey Clinical Medical Research Award honors three scientists for their discovery and development of GLP-1-based drugs that have revolutionized the treatment of obesity

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Shiloach J, Kaufman J, Guillard AS, Fass R

Essential Monitoring and Patient Counseling: If combination therapy is pursued, providers should ensure: Close monitoring for gastrointestinal tolerability Vitamin supplementation (multivitamin with fat-soluble vitamins taken 2 hours from orlistat) Clear instructions on timing (orlistat with fat-containing meals, skip if meal is skipped or fat-free