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No tolerance development or suppressive effects on natural healing processes have been observed in research

However, another randomized, double-blind, placebo-controlled trial in 181 patients with diabetic neuropathy found that oral supplementation with either 600 mg/day, 1,200 mg/day, or 1,800 mg/day of lipoic acid for five weeks significantly improved neuropathic symptoms (77)

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Participants receiving 2.4mg weekly semaglutide lost an average of 14.9% of their body weight over 68 weeks, compared to 2.4% in the placebo group