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doi: 10.2337/db20-0375 197 BarberAJ

DNA repair and damage response BRCA2 BRCA2 has not typically been associated with low mutational burden in GBM, with expression of BRCA1 and BRCA2 mutant GBM found in 1.4% of patient cases [49]

This molecule is a tripeptide, which means it is made of three specific amino acids: cysteine, glycine, and glutamic acid

Lastly, a triad of vascular abnormalities is observed, including pathological angiogenesis, abnormal endothelial cell proliferation and intravascular thrombosis (17,18)