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More recent evidence is expanding their benefits to heart failure with preserved ejection fraction and clinically important renal outcomes in patients with and without diabetes

Glucagon-like peptide-1 decreases endogenous amyloid- peptide (A) levels and protects hippocampal neurons from death induced by A and iron

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For each ligand, LigandScout initially identified all potential pharmacophoric features, including hydrogen bond donors/acceptors, aromatic interactions, hydrophobic regions, and charged or ionizable groups

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