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Microbiology and molecular biology reviews: MMBR

GLP-1 exerts its effects through the GLP-1 receptor (GLP-1R) in multiple tissues, including the pancreas, kidneys, adipose tissue, brain, and smooth muscles [14]

Cardiovascular benefits including lower blood pressure and reduced inflammatory markers were observed even in patients without baseline diabetes

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(Trump reversed that effort this year, barring Medicare and Medicaid from using them to treat the disease of obesity.) This plan to simplify payments and expand access would not make all drugs affordable in the United States, but increasing accessibility to GLP-1s can get us on the road to eliminating the significant problem of cardiometabolic disease and improving our health