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Pesticides and oxidative stress: a review

10.1002/1099-1573(200006)14:4%3C235::AID-PTR574%3E3.0.CO;2-G 216

A total of 16 participants were enrolled, all of whom were women with a median age of 64 years (range of 2588 years)

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And GAS could block the mitogen-activated protein kinases (MAPK) signal pathway, and suppress the inflammatory mediators such as cyclic adenosine monophosphate (cAMP)-response element binding protein (CREB) and nuclear factor kappa-B (NF-B) phosphorylation, in PTZ-treated epileptic mice [35, 36]