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PMID: 28831150 Guo XH (2016): The value of short- and long-acting glucagon-like peptide-1 agonists in the management of type 2 diabetes mellitus: experience with exenatide

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The effects of apoptosis stimulation were confirmed to occur only in cells expressing GLP-1R in a gain-of-function experiment ( 4.2 Hepatic metabolic modulation effects by GLP-1RAs GLP-1RAs replicate the action of the incretin hormone GLP-1, which primarily involves boosting insulin release, reducing glucagon secretion, and increasing feelings of fullness, ultimately leading to improved glycemic control and supporting weight management (Xu et al., 2024)

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