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Unfortunately, a phase II clinical trial of UBX0101 (NCT03513016) was completed in patients with osteoarthritis and the promising results observed (Table 1), in vitro and in vivo, have not been up to the expectations in treated patients, leading only to a decrease of pain, without a significant improvement of the disease 30

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A holistic approach combining diet, lifestyle, and sometimes strategic supplementation or IV therapy may be needed for optimal levels

Mechanistic Target: Often utilized in model systems to observe fibroblast migration and soft tissue healing pathways

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