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This sequence of events is similar to when Trkb is removed from striatal iSPNs and supports the idea of GSTO2 being a putative disease-modifying enzyme that could be targeted in the early stages of HD

Beyond the astrocytic activation by TDP-43, pericytes, astrocytes, and microglia regulate the infiltration of peripheral immune cells

OGT-mediated O-GlcNAcylation promotes NF-kappaB activation and inflammation in acute pancreatitis

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