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doi: 10.3389/fimmu.2023.1109122 80 LeeSYooICheonYChoiEKimSKaH

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267 Other randomized controlled trials have found supplementing with EPA plus DHA reduced anxiety symptoms in heart attack patients, 268 women with premenstrual syndrome, 269 and individuals with substance abuse histories

COX-2 catalyzes the synthesis of prostaglandin E 2 (PGE 2 ) (Ilari et al., 2020), while iNOS produces nitric oxide (NO), which together contribute to the formation of reactive nitrogen species (RNS) (Zhao et al., 2022), thereby exacerbating tissue inflammation and oxidative injury

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