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If pain, range of motion, or function has not moved by week 4, the dose or delivery method needs adjusting rather than extending the same protocol blindly

Post-laser healing (13 patients): Topical copper tripeptide complex applied after CO2 laser resurfacing was evaluated for accelerated healing and reduced erythema (PMID 16847171)

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TLR9-mediated effects in mature erythrocytes include activation of erythrophagocytosis and enhancement of the innate immune response [55, 56]

With respect to safety, the systematic review by Zamawe and colleagues found no statistically significant differences in the rate of hemorrhage, caesarean section, assisted vaginal delivery, referral to neonatal intensive care unit, meconium-stained liquor, maternal death, stillborn, and uterine rupture between users and non-users of castor oil (Zamawe et al., 2018)