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The peptide is delivered through the nasal passages and absorbed into the bloodstream

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Ethics declarations Ethics approval and consent to participate The study protocol was conducted according to the guidelines contained within the Declaration of Helsinki and was approved by the ethics committees of Yokohama City University and Kyoto Prefectural University

Ipamorelin (NNC 26-0161) Ipamorelin is a pentapeptide growth hormone secretagogue receptor agonist that acts via the GHS-R1a the ghrelin receptor located in the hypothalamus and pituitary

Secretion, degradation, and elimination of glucagon-like peptide 1 (GLP-1) and gastric inhibitory polypeptide (GIP) in patients with chronic renal insufficiency and healthy controls