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Indeed, GLP-1 RA users in our cohort exhibited more frequent risk factors for pancreatic cancerincluding older age, obesity, type 2 diabetes, and prior gastrointestinal disorderssuggesting a background of increased vulnerability

reported that GLP-1RAs can promote the overactivation of GLP-1R in pancreatic cells, which not only increases susceptibility to pancreatic inflammation but also increases the risk of pancreatic cancer

Following is a list of the current FDA-approved GLP-1 agonists being prescribed for type 2 diabetes and/or weight loss

At STRIPE, we are working to advance standards for pharmacogenomics testing, data integration, and clinical decision support so that genetic information can be reliably used to improve medication safety and effectiveness

doi: 10.1016/j.metabol.2024.156113