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This exacerbates retinal leakage and ischemia, leading to severe NPDR (stage 3), characterized by extensive DBH across all four quadrants, venous beading (VB), and intraretinal microvascular abnormalities (IRMA)

This synergistic integrationusing AI for rapid stratification, multi-omics for deep phenotyping, and targeted systems for precise treatmentforms the definitive framework for translating our understanding of oxidative stress into meaningful clinical benefit and finally fulfilling the unmet promise of MIRI therapy

Data are mean (SD), median [interquartile range], or n (%)

The intestinal absorption is mediated by the DMT-1 transporter and increases with the deficient intake of iron (Fe) and zinc (Zn)

doi: 10.1007/BF00401150 22 Action to Control Cardiovascular Risk in Diabetes Study GroupGersteinHCMillerMEByingtonRPGoffDCJrBiggerJTet al