(69) demonstrated that 14-day exposure to a eucaloric very-low-carbohydrate ketogenic diet as adjuvant treatment to first-generation somatostatin receptor ligands decreased IGF-I without increasing GH levels in acromegaly patients

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These anti-inflammatory effects of curcumin in Metabolic Syndrome patients have been consistently observed in clinical studies (Gorabi et al., 2022)
Notably, enzymes such as aldehyde dehydrogenases (ALDHs) and glutathione S-transferases (GSTs) maintained relatively high expression at Day 45, possibly supporting metabolic adaptation to a diverse cellular environment
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