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4mg (weeks 9-12): This is often described as the first significant dose by researchers

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The use of intralipid emulsion should be considered in patients who have consumed lipophilic TCAs in overdose and are hemodynamically unstable.[] Specific measures for benzodiazepine overdose In terms of assessment, due care must be taken to maintain airways, prevent and manage respiratory depression, and prevent aspiration pneumonia

Finally, NAC/THC co-exposure significantly increased PFC arginine levels