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The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy

JCI Insight 7, e159863

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The Systematic Multi-Domain Alzheimer Risk Reduction Trial (SMARRT) applied this approach to its intervention group, allowing participants (cognitively healthy older adults at high risk for dementia) to select and set personalized risk-reduction goals based on their personal risk profile, preferences, and priorities for risk reduction