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Higher concentrations mean smaller injection volumes, which generally means less discomfort

Ethics approval was not required for this literature review as it did not involve any primary research with human subjects

P., Kaneko, S., Lee, C

Semaglutide features a substitution of alanine residue with a non-coded amino acid, 2-aminoisobutyric acid (Aib) at position 8, shielding against DPP-4-mediated N-terminal proteolysis while preserving GLP-1R affinity (96)