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Description

The interaction between AGEs and their receptors not only activates NF-B to drive an explosive secretion of cytokines but also forms a cytokine storm that chemotactically recruits CD4+ T cells into the renal interstitium, amplifying local inflammation

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The dosage protocol matters because TB-500s mechanism relies on sustained tissue signaling rather than a single acute dose

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A secondary outcome of the randomized, double-blind, placebo-controlled study

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