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Ongoing clinical trials, such as SUMMIT (NCT04847557), aim to validate these preclinical findings

However, long-term use in healthy athletes hasnt been studied extensively, so risks around glucose tolerance, joint pain, or GH-related issues remain

A good starting point is to sip fluids consistently throughout the day and pay attention to signs such as dark urine, dry mouth, dizziness, headache, fatigue, or constipation

Its antiinflammatory properties also improve minor imperfections such as red spots, rough patches and acne

We also thank Translational Medicine Core Facility and Core facility of school of basic medical sciences of Shandong University for consultation and instrument availability that supported this work