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doi: 10.1093/ajcn/nqaa177 252 SekharR

Semaglutide targets one pathway (GLP-1), retatrutide targets three hormone pathways (GLP-1, GIP, and glucagon)

[89] Ocular side effects may include increased intraocular pressure, cataract formation, and increased risk of ocular infections

Evidence includes: Stimulation of endothelial and keratinocyte migration Enhanced blood vessel density in wound healing models Promotion of stem cell differentiation toward repair cell lineages Low molecular weight enabling tissue penetration over long distances Unlike growth factors that bind to extracellular matrix, TB-500s mobility allows systemic distribution to multiple injury sites

Animals were anesthetized intramuscularly with a ketaminexylazine mixture composed of 30 mg/kg ketamine and 12 mg/kg xylazine, respectively, with a total injection volume of 1.2 mL/kg