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The research protocol should be reviewed and dose reduction or timing adjustment considered

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FIGURE 5 Kim and colleagues conducted a study on the wound-healing properties of pinitol in lipopolysaccharide-induced human dermal fibroblasts and streptozotocin-induced diabetic rat models with foot wounds and found that pinitol reduced oxidative stress by enhancing the nuclear translocation of Nrf2 and markedly upregulating antioxidant enzymes like HO-1, SOD1, SOD2, and catalase (Kim et al., 2024)