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Bezafibrate in skeletal muscle fatty acid oxidation disorders: a randomized clinical trial

The study projected 93 million U.S

This resulted in Sirt3 upregulation, sustained deacetylation of p53, PGC-1, Foxo1, NF-B, and the inhibition of oxidative stress and apoptosis in the infarcted myocardium

Nausea is most pronounced during dose escalation windows, particularly around weeks six to eight when doses are increasing, and typically diminishes substantially by week twelve as tolerance develops