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The values of K m, V max and k cat of TyrBm in the presence of HQ as a substrate were determined with the following conditions: 50 mM PBS buffer pH 7.4, 0.01 mM CuSO 4 , 6 g ml 1 of purified enzyme, various concentrations of HQ (0.12.0 mM) in the presence of saturating concentration of hydrogen peroxide (100 mM) 51
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Mazdutide's Phase 3 safety database is substantially larger, showing mostly mild to moderate GI events with no new safety signals when compared head-to-head with semaglutide in DREAMS-3
It is intended for daily use with a strong safety profile and minimal reported side effects when used as directed
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