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In a perfect world, GLP-1s could help reduce the inequities in obesity and relieve underfunded healthcare systems of a great burden

Biomed Pharmacother 111:926933 Duparc T, Briand F, Trenteseaux C, Merian J, Combes G, Najib S, Sulpice T, Martinez LO (2019) Liraglutide improves hepatic steatosis and metabolic dysfunctions in a 3-week dietary mouse model of nonalcoholic steatohepatitis

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HGF/c-Met and the RAS/MAPK signaling pathway As mentioned above, the RAS/MAPK pathway is also considered a downstream effector of HGF/c-Met signals, among other signal transduction pathways [86, 121]

Some compounds have strong mechanistic logic but thin clinical evidence