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Combination potential: stacking and synergy One of the most important differences between cagrilintide and retatrutide is their potential for combination therapy

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Activation of GIP receptors and GLP-1 remains a focus of research due to their involvement in glucose-dependent insulin secretion, modulation of glucagon secretion, regulation of gastric emptying and mechanisms related to the control of satiety and energy intake

We also highlight that obesity itself may affect the sense of taste by distinct molecular mechanisms

Some outcomes are already supported by large trials