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68 The widespread use of GLP-1RAs has raised concerns about their safety profile

In the brain, it activates GLP-1 receptors in the hypothalamus reducing hunger signals and increasing satiety, so that you feel full sooner and satisfied longer after eating, naturally reducing caloric intake without the psychological struggle of rigid dieting

A study in JAMA Internal Medicine looked at the body weight loss (measured in percent of body weight) between semaglutide and tirzepatide at 3, 6, and 12 months

[DOI] [PubMed] [Google Scholar] 12.Molonon B.R., Bowers J.A., Dayton A.D

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