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In 2 series of patients with obesity and MASLD with advanced fibrosis, balloon placement resulted in significant weight loss (mean total body weight loss 11.7% at 6 months in 1 study) 39 and reductions in liver stiffness and fibrosis-4 index scores

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Hormonal Recovery and System Reset While traditional SERM-based PCT (e.g., Clomid, Nolvadex) may not be necessary after HGH or IGF-1 LR3 alone, users should still support: Liver and metabolic health Insulin sensitivity restoration Endogenous IGF-1 balance Testosterone production (if steroids were included) Prolonged use of IGF-1 analogs may lead to negative feedback on GH/IGF axis and necessitate time off or tapering for hormonal normalization. Baxter, R