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doi: 10.1017/s0033291721000155 178 akiciNSutterlandALPenninxBDalmVAde HaanLvan BeverenNJM

GGT1 knockdown cell lines had minimal GGT1 mRNA (Extended Data Fig

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On the same hand, the metastasis suppressor N-myc downstream regulated gene 1 (NDRG1) interrupted tumorigenic bidirectional crosstalk between pancreatic cancer cells and stromal pancreatic stellate cells, major contributors to local tumor growth and metastasis, partly through inhibition of IGF-1 and other potent mediators of cell migration, including hepatocyte growth factor (HGF) (33) ( Figure 3 )

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