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doi: 10.1111/j.1365-2222.1991.tb00831.x
Serine metabolism in health and disease and as a conditionally essential amino acid
Yuan, B
Full optimization may take a few months and often improves after the second pellet cycle
They concluded current evidence of the skin-whitening effect of glutathione is still inconclusive however there is a trend that glutathione might brighten skin colour at sun-exposed area. A review specifically focusing on topical glutathione (and melanogenesis) found that though topical forms (e.g., GSH 0.5% vs 0.1%) had more effect, the studies were small, short term and lack longterm data
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