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Coskuns research contributions include: Preclinical characterization of GLP2s dual receptor agonism and pharmacological properties Elucidation of the complementary mechanisms by which GIP and GLP-1 receptor activation produce synergistic metabolic effects Investigation of GLP2s effects on glucose homeostasis, body weight regulation, and energy expenditure in animal models Development of the scientific rationale supporting GLP2s advancement into human clinical trials Publication of seminal research establishing GLP2s unique pharmacological profile as an imbalanced dual agonist His work has contributed significantly to advancing understanding of incretin biology and establishing GLP2 as the prototype for a new therapeutic class in metabolic disease treatment
Hallucinations (seeing/hearing things that arent there) Delusions (false beliefs about things that are not based in reality) Hypomania/mania (periods of excessive energy or irritability that can lead to extreme risk-taking behaviors and impaired thought processes) Suicidal thoughts Additionally, taking Lexapro with certain medications or herbs may increase serotonin activity to dangerous levels, leading to serotonin syndrome
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