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Researchers studied AOD-9604 to see whether the fat-metabolism part of growth hormone could work without the muscle-building, blood-sugar, and IGF-1 effects of the full hormone

Lu, S., Yin, H., Yu, O

The vessel normalization hypothesis, introduced by Rakesh Jain in 2001 [308] suggests that rather than depleting vessels, a sub-maximal doses of anti-angiogenic therapy can restore the normal function and structure of tumor vessels and improve drug delivery