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This is significant because, if a single valid vector can be identified (see below for criteria), it demonstrates that somatic and affective symptoms have a common core and, hence, a shared pathophysiology [25]
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The observed sex dimorphism in inflammatory cytokines was a particularly intriguing and unexpected observation, which beyond serving as a marker of aging status, could be reflective of the relative increase and decrease in neoplasms, documented in male and female mice, respectively
In addition, there are some genetic variations (mutations) that can increase the chance of developing Parkinsons, but people who have these mutations do not always develop this disease