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(2003) on db/db diabetic and aged mice, and the Sosne corneal series (2002, 2005, 2010) form a coherent body of work demonstrating accelerated re-epithelialization, reduced inflammatory infiltration, and improved wound closure with topical, SC, or IM administration

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First, it was retrospective, which means it relied on patients recalling their experiences months laterthis is far less reliable than a controlled, prospective study

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