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Inflammation and peripheral nerve injury increase NGF expression and sensitise peripheral nociceptive terminals through the induction of gene expression in nociceptors [28]

While promising in research for fat metabolism and potentially cartilage repair, large trials showed good efficacy with AOD9604 for obesity, but it remains a research tool for studying fat burning and metabolic pathways, often used off-label in wellness settings alongside diet and exercise with promising affects for cartilage repair

Supplementation may be used as part of a nutritional wellness protocol for individuals seeking additional metabolic or energy support

Archived from the original on 12 September 2018

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