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Despite the heavy economic burden, cancer remains a complex global problem, and stands as the second leading cause of mortality in the United States, underscoring the complexity and pervasiveness of this disease (259)

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Among them, NLRP3 inflammasomes are the most intensively investigated, commonly present in neutrophils, monocytes, dendritic cells, macrophages, and non-hematopoietic cells

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This article explores the possible negative side effects, regulatory considerations, and medical factors that should be evaluated before starting peptide therapy, especially for individuals seeking long-term health improvements