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These investigations suggest that increased intracellular superoxide production in the subfornical organ is critical to the development of AT-II-induced hypertension
Statistical significance was assessed by an unpaired two-tailed t-test in a - i , l - n , and by Ordinary One-Way ANOVA followed by Dunnetts multiple comparisons test in j , k
In conclusion, these findings demonstrate that a clinical intervention for 3-months with oral L-GSH in individuals with T2DM can decrease levels oxidized GSH, while maintaining levels of reduced GSH and overall reducing the extent of oxidative stress
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