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The process of safely delivering copper to these enzymes is complex, and disruption of this process can lead to disease, particularly neu-rodegenerative disease

The full chemical sequence is Aib-His-D-2-Nal-D-Phe-Lys-NH2, where Aib is -aminoisobutyric acid, D-2-Nal is D-2-naphthylalanine, and the C-terminal lysine carries an amide cap

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Usually, CR involves a 2050% reduction in energy intake while maintaining sufficient intake of essential vitamins and minerals

V., Zamboni, P., & Mahajan, R