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Cabrera, Margarita et al

Tirzepatide cyclists experience dual-pathway metabolic changes: the medication activates GLP-1 and GIP receptors to slow gastric emptying and reduce appetite signaling, while sustained aerobic training increases insulin sensitivity and shifts substrate utilization toward fat oxidation

Notably, the PtMnIr nanozyme exhibits multiple enzymatic activities, integrating OXD, CAT, SOD, POD, and GPX functionalities, thereby promoting ferroptosis and apoptosis in tumour cells while inhibiting tumour metastasis by establishing an endogenous GSH consumptionROS cyclic generation mechanism [139]

PMID: 18164447 Locigno R1, Pincemail J, Henno A, et.al