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A similar effect was observed when cyclosporin A was replaced by the polyamine L-carnitine (slope 0.29 vs 0.53, P = 0.004) (Fig

Thus, in addition to a comprehensive approach encompassing multidisciplinary risk factors (dyslipidaemia, hypertension, obesity, smoking, etc.) [8, 9], considering "what drugs to use to lower blood glucose" by selecting hypoglycaemic agents with evidence-based cardiorenal protective effects, according to patient background and risk status is increasingly important [10]