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W.FukaiT.et al (2007)

The oral administration of approximately equimolar doses of chlorothalonil (75 mg/kg per day) or the monoglutathione conjugate of chlorothalonil (150 mg/kg per day) resulted in significantly increased kidney weight and in treatment-related histopathological changes in the kidney

The enhanced hepatic mitochondrial activity in the context of TKT deficiency has been shown to be the result of increased phospholipid synthesis, particularly increased synthesis of phosphatidylcholine which represents the major phospholipid in the mitochondrial membrane

10.1016/j.jns.2006.03.006 J

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