Available under names like Wegovy for weight management, and Ozempic for type 2 diabetes, semaglutide offers a dual-action plan
The preclinical research is not trivial, and legitimate questions about potential applications in tendon repair, gut healing, and neuroprotection merit serious investigation
Ann Intern Med 159(2):130137
While GLP-1 receptor agonists have reshaped the treatment landscape, the next decade promises further diversification, driven by oral agents, innovative delivery mechanisms, and combination therapies
A patient on "the best" GLP-1 medication (by name) who titrates too quickly, skips doses, or stops at the first side effect will have worse outcomes than a patient on "the worst" GLP-1 medication who titrates slowly, stays consistent, and reaches maintenance dose