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Description

CANCER CELLS OFTEN HIJACK THE KEAP1NRF2 SYSTEM Intriguingly, various human cancers frequently exhibit increased levels of NRF2 (Singh et al., 2006

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13,14,15,16,17,18 Currently, the disease can only be diagnosed by DNA sequencing, and only a subset of individuals have detectable reductions in Asn levels in serum and cerebrospinal fluid, hindering the use of this test for initial screening

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Other inhibitors Paricalcitol restores GPX4 expression by activating VDR, improves renal function, reduces mitochondrial damage, and alleviates cisplatin-induced AKI [163, 171, 179]

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