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Additional tests may include full blood count (to check for macrocytic anaemia), methylmalonic acid and homocysteine levels (which rise in B12 deficiency), and tests for intrinsic factor antibodies if pernicious anaemia is suspected

The erythroblasts were treated with hemin (75 M), the oxidized form of heme, under hypoxic condition (1% O 2 ), with or without 50 M DMF in a two-phase culture system 31 (Supplementary Fig

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